3D printing technology for tissue: Researcher

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February 7, 2024
This article has been reviewed according to Science X’s editorial process and policies. Editors have highlighted the following attributes while ensuring the content’s credibility:
fact-checked
trusted source
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by Jennifer Opel, Bayreuth University
In the latest study by Prof. Dr. Leonid Ionov, Professor of Biofabrication, and his team at the University of Bayreuth, various types of hydrogels were extensively tested for the 3D printing of tissues. A hydrogel is a water-retaining and also water-insoluble polymer. In addition, the cell containing–hydrogels, also known as bioink, are combined with fibers to create a composite material.
This is achieved by using 3D (bio) printing with an integrated touch-spinning process. Touch spinning is a scalable process for producing fibers from a polymer solution or melt. The Bayreuth scientists have now combined 3D (bio) printing technology with touch-spinning technology in a single device for the first time.
“The insights gained in this study are of great importance for the production of tissues and in particular tissues with fibrous structures and uniaxial alignment of cells such as connective and muscle tissue,” explains Prof. Dr. Ionov.
In their article recently published in the journal Advanced Healthcare Materials, Prof. Dr. Ionov, along with Bayreuth researchers Prof. Dr. Dr. Elisabetta Ada Cavalcanti-Adam, Chair of Cellular Biomechanics, Waseem Kitana, Ph.D. student at the Chair of Biofabrication, and their colleague Dr. Victoria Levario-Diaz from the Max Planck Institute for Medical Research, report on a novel approach for the production of multilayer bioink fiber composites.
The Bayreuth scientists used various hydrogels in the experiments and compared their properties. Hydrogels have been widely used as scaffold materials in the fields of tissue engineering and biofabrication for decades. Tissue engineering is the umbrella term for the artificial production of biological tissues.
The combination of a hydrogel system with a fiber system reduces the processing requirements for hydrogels, such as cross-linking to improve their mechanical properties, as the mechanical properties of these composite materials are covered by the fiber system. In addition, the requirement for a low degree of cross-linking is advantageous for subsequent tissue formation.
“The hydrogel provides the cells with an aqueous environment that promotes the good functioning of the cells, while the fibers should control the orientation of the cells along the main direction of the fiber,” says Prof. Dr. Ionov.
More information: Waseem Kitana et al, Biofabrication of Composite Bioink‐Nanofiber Constructs: Effect of Rheological Properties of Bioinks on 3D (Bio)Printing and Cells Interaction with Aligned Touch Spun Nanofibers, Advanced Healthcare Materials (2023). DOI: 10.1002/adhm.202303343
Provided by Bayreuth University
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source3D printinindia3D printinchina3D printinusa3D printin
Canada3D printinkuwait3D printinAntigua and Barbuda
3D printinArgentina3D printinArmenia
3D printin
Australia
3D printinAustria
3D printinAustrian Empire*
Azerbaijan
3D printinBaden*
Bahamas, The
3D printinBahrain
3D printinBangladesh
3D printinBarbados
3D printinBavaria*
3D printinBelarus
3D printinBelgium
3D printinBelize
3D printinBenin (Dahomey)
3D printinBolivia
3D printinBosnia and Herzegovina
3D printinBotswana
3D printinBrazil
3D printinBrunei
3D printinBrunswick and Lüneburg*
3D printinBulgaria
3D printinBurkina Faso
3D printinBurma
3D printinBurundi
3D printinCabo Verde
3D printinCambodia
3D printinCameroon
3D printinCanada
3D printinCayman Islands, The
3D printinCentral African Republic
3D printinCentral American Federation*
3D printinChad
3D printinChile
3D printinChina
China
3D printinColombia
3D printinComoros
3D printinCongo Free State, The*
3D printinCosta Rica
3D printinCote d’Ivoire
3D printinCroatia
3D printinCuba
3D printinCyprus
3D printinCzechia
3D printinCzechoslovakia*
3D printinDemocratic Republic of the Congo
3D printinDenmark
3D printinDjibouti
3D printinDominica
3D printinDominican Republic
3D printinDuchy of Parma, The*
3D printinEast Germany German Democratic Republic*
3D printinEcuador
3D printinEgypt
3D printinEl Salvador
3D printinEquatorial Guinea
3D printinEritrea
3D printinEstonia
3D printinEswatini
3D printinEthiopia
3D printinFederal Government of Germany *
3D printinFiji
3D printinFinland
3D printinindia3D printinchina3D printinusa3D printin
Canada3D printinkuwait3D printinAntigua and Barbuda
3D printinArgentina3D printinArmenia
3D printin
Australia
3D printinAustria
3D printinAustrian Empire*
Azerbaijan
3D printinBaden*
Bahamas, The
3D printinBahrain
3D printinBangladesh
3D printinBarbados
3D printinBavaria*
3D printinBelarus
3D printinBelgium
3D printinBelize
3D printinBenin (Dahomey)
3D printinBolivia
3D printinBosnia and Herzegovina
3D printinBotswana
3D printinBrazil
3D printinBrunei
3D printinBrunswick and Lüneburg*
3D printinBulgaria
3D printinBurkina Faso (Upper Volta)
3D printinBurma
3D printinBurundi
3D printinCabo Verde
3D printinCambodia
3D printinCameroon
3D printinCanada
3D printinCayman Islands, The
3D printinCentral African Republic
3D printinCentral American Federation*
3D printinChad
3D printinChile
3D printinChina
China
3D printinColombia
3D printinComoros
3D printinCongo Free State, The*
3D printinCosta Rica
3D printinCote d’Ivoire
3D printinCroatia
3D printinCuba
3D printinCyprus
3D printinCzechia
3D printinCzechoslovakia*
3D printinDemocratic Republic of the Congo
3D printinDenmark
3D printinDjibouti
3D printinDominica
3D printinDominican Republic
3D printinDuchy of Parma, The*
3D printinEast Germany
3D printinEcuador
3D printinEgypt
3D printinEl Salvador
3D printinEquatorial Guinea
3D printinEritrea
3D printinEstonia
3D printinEswatini
3D printinEthiopia
3D printinFederal Government of Germany *
3D printinFiji
3D printinFinland
Click here to sign in with or
Forget Password?
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79
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February 7, 2024
This article has been reviewed according to Science X’s editorial process and policies. Editors have highlighted the following attributes while ensuring the content’s credibility:
fact-checked
trusted source
proofread
by Jennifer Opel, Bayreuth University
In the latest study by Prof. Dr. Leonid Ionov, Professor of Biofabrication, and his team at the University of Bayreuth, various types of hydrogels were extensively tested for the 3D printing of tissues. A hydrogel is a water-retaining and also water-insoluble polymer. In addition, the cell containing–hydrogels, also known as bioink, are combined with fibers to create a composite material.
This is achieved by using 3D (bio) printing with an integrated touch-spinning process. Touch spinning is a scalable process for producing fibers from a polymer solution or melt. The Bayreuth scientists have now combined 3D (bio) printing technology with touch-spinning technology in a single device for the first time.
“The insights gained in this study are of great importance for the production of tissues and in particular tissues with fibrous structures and uniaxial alignment of cells such as connective and muscle tissue,” explains Prof. Dr. Ionov.
In their article recently published in the journal Advanced Healthcare Materials, Prof. Dr. Ionov, along with Bayreuth researchers Prof. Dr. Dr. Elisabetta Ada Cavalcanti-Adam, Chair of Cellular Biomechanics, Waseem Kitana, Ph.D. student at the Chair of Biofabrication, and their colleague Dr. Victoria Levario-Diaz from the Max Planck Institute for Medical Research, report on a novel approach for the production of multilayer bioink fiber composites.
The Bayreuth scientists used various hydrogels in the experiments and compared their properties. Hydrogels have been widely used as scaffold materials in the fields of tissue engineering and biofabrication for decades. Tissue engineering is the umbrella term for the artificial production of biological tissues.
The combination of a hydrogel system with a fiber system reduces the processing requirements for hydrogels, such as cross-linking to improve their mechanical properties, as the mechanical properties of these composite materials are covered by the fiber system. In addition, the requirement for a low degree of cross-linking is advantageous for subsequent tissue formation.
“The hydrogel provides the cells with an aqueous environment that promotes the good functioning of the cells, while the fibers should control the orientation of the cells along the main direction of the fiber,” says Prof. Dr. Ionov.
More information: Waseem Kitana et al, Biofabrication of Composite Bioink‐Nanofiber Constructs: Effect of Rheological Properties of Bioinks on 3D (Bio)Printing and Cells Interaction with Aligned Touch Spun Nanofibers, Advanced Healthcare Materials (2023). DOI: 10.1002/adhm.202303343
Provided by Bayreuth University
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Feb 7, 2024
Feb 7, 2024
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More from Biology and Medical
Sep 19, 2022
Nov 6, 2023
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Feb 8, 2024
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Thank you for taking time to provide your feedback to the editors.
Your feedback is important to us. However, we do not guarantee individual replies due to the high volume of messages.
Your email address is used only to let the recipient know who sent the email. Neither your address nor the recipient’s address will be used for any other purpose. The information you enter will appear in your e-mail message and is not retained by Phys.org in any form.

Get weekly and/or daily updates delivered to your inbox. You can unsubscribe at any time and we’ll never share your details to third parties.
More information Privacy policy
We keep our content available to everyone. Consider supporting Science X’s mission by getting a premium account.
Medical research advances and health news
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The most comprehensive sci-tech news coverage on the web

source3D printinindia3D printinchina3D printinusa3D printin
Canada3D printinkuwait3D printinAntigua and Barbuda
3D printinArgentina3D printinArmenia
3D printin
Australia
3D printinAustria
3D printinAustrian Empire*
Azerbaijan
3D printinBaden*
Bahamas, The
3D printinBahrain
3D printinBangladesh
3D printinBarbados
3D printinBavaria*
3D printinBelarus
3D printinBelgium
3D printinBelize
3D printinBenin (Dahomey)
3D printinBolivia
3D printinBosnia and Herzegovina
3D printinBotswana
3D printinBrazil
3D printinBrunei
3D printinBrunswick and Lüneburg*
3D printinBulgaria
3D printinBurkina Faso
3D printinBurma
3D printinBurundi
3D printinCabo Verde
3D printinCambodia
3D printinCameroon
3D printinCanada
3D printinCayman Islands, The
3D printinCentral African Republic
3D printinCentral American Federation*
3D printinChad
3D printinChile
3D printinChina
China
3D printinColombia
3D printinComoros
3D printinCongo Free State, The*
3D printinCosta Rica
3D printinCote d’Ivoire
3D printinCroatia
3D printinCuba
3D printinCyprus
3D printinCzechia
3D printinCzechoslovakia*
3D printinDemocratic Republic of the Congo
3D printinDenmark
3D printinDjibouti
3D printinDominica
3D printinDominican Republic
3D printinDuchy of Parma, The*
3D printinEast Germany German Democratic Republic*
3D printinEcuador
3D printinEgypt
3D printinEl Salvador
3D printinEquatorial Guinea
3D printinEritrea
3D printinEstonia
3D printinEswatini
3D printinEthiopia
3D printinFederal Government of Germany *
3D printinFiji
3D printinFinland
3D printinindia3D printinchina3D printinusa3D printin
Canada3D printinkuwait3D printinAntigua and Barbuda
3D printinArgentina3D printinArmenia
3D printin
Australia
3D printinAustria
3D printinAustrian Empire*
Azerbaijan
3D printinBaden*
Bahamas, The
3D printinBahrain
3D printinBangladesh
3D printinBarbados
3D printinBavaria*
3D printinBelarus
3D printinBelgium
3D printinBelize
3D printinBenin (Dahomey)
3D printinBolivia
3D printinBosnia and Herzegovina
3D printinBotswana
3D printinBrazil
3D printinBrunei
3D printinBrunswick and Lüneburg*
3D printinBulgaria
3D printinBurkina Faso (Upper Volta)
3D printinBurma
3D printinBurundi
3D printinCabo Verde
3D printinCambodia
3D printinCameroon
3D printinCanada
3D printinCayman Islands, The
3D printinCentral African Republic
3D printinCentral American Federation*
3D printinChad
3D printinChile
3D printinChina
China
3D printinColombia
3D printinComoros
3D printinCongo Free State, The*
3D printinCosta Rica
3D printinCote d’Ivoire
3D printinCroatia
3D printinCuba
3D printinCyprus
3D printinCzechia
3D printinCzechoslovakia*
3D printinDemocratic Republic of the Congo
3D printinDenmark
3D printinDjibouti
3D printinDominica
3D printinDominican Republic
3D printinDuchy of Parma, The*
3D printinEast Germany
3D printinEcuador
3D printinEgypt
3D printinEl Salvador
3D printinEquatorial Guinea
3D printinEritrea
3D printinEstonia
3D printinEswatini
3D printinEthiopia
3D printinFederal Government of Germany *
3D printinFiji
3D printinFinland